The 2025-26 Ghana Premier League got underway on Friday, September 12, 2025, with exciting matches that set the tone for an thrilling season. Here are the results:

Hearts of Oak endured a frustrating start to the season, settling for a goalless draw against newly promoted Hohoe United. Despite dominating possession, the Phobians struggled to carve out clear-cut opportunities.

Reigning champions Bibiani Gold Stars launched their title defense with a hard-fought 2-1 victory over Bechem United. Samuel Atta Kumi scored twice in the opening 22 minutes to give Gold Stars a decisive lead.
Asante Kotoko ended a 15-year wait for an away league win at Berekum Chelsea, edging a tight contest 1-0. Albert Amoah’s decisive goal midway through the second half gave the Porcupine Warriors a precious lead.

Other Results:
- Medeama SC 2-0 Young Apostles: Medeama surged to the top of the table with a 2-0 win, thanks to goals from Mensah Jacob Amu and Paul Yeboah.
- Karela United 1-0 Aduana FC: Karela secured a narrow 1-0 win, with Malik Abubakar’s early goal proving decisive.
- Nations FC 2-1 Swedru All Blacks: Nations FC came from behind to win 2-1, with Emmanuel Annor scoring a stoppage-time winner.
- Heart of Lions 1-0 Dreams FC: Heart of Lions won 1-0, with Ebenezer Abban’s penalty proving decisive.
- Vision FC 0-0 FC Samartex: Vision FC held FC Samartex to a goalless draw despite finishing with ten men.
- Basake Holy Stars 0-0 Eleven Wonders: Basake Holy Stars and Eleven Wonders played out a stalemate.

